From: Guidelines for treatment of immune-mediated cerebellar ataxias
Gluten ataxia |
Induction and maintenance therapies: strict gluten-free diet |
(In case of no improvement and negative gluten related antibodies, immunosuppressants or IVIg ) |
Paraneoplastic cerebellar degeneration |
Quick removal of neoplasm must be the first objective of treatment |
Induction therapy as soon as possible: mPSL, IVIg, immunosuppressants, or/and plasma exchange |
Discussion according associated Abs |
Maintenance therapy: continuous oral PSL, IVIg, immunosuppressants |
Anti-GAD Abs associated cerebellar ataxia |
Induction therapy: mPSL, IVIg, immunosuppressants, plasma exchange, or/and rituximab |
Maintenance therapy: continuous oral PSL, IVIg, immunosuppressants, or/and rituximab |